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Staging & Prognostic Factors Flashcards

7 cards from real CTR practice questions. Tap to flip, then mark Knew It or Still Learning โ€” missed cards come back until you master them.

Read the first 7 Staging & Prognostic Factors flashcards as text
  1. In prostate cancer staging, what Gleason score range indicates Grade Group 5 (the highest grade)?

    Answer: Gleason 9-10

    Grade Group 5 encompasses Gleason scores 9 and 10, representing the most poorly differentiated prostate tumors.

  2. Which SEER summary stage category is used when cancer has spread only to regional lymph nodes with no distant spread?

    Answer: Regional

    SEER 'Regional' stage is assigned when cancer has spread to nearby lymph nodes or tissues but not to distant sites.

  3. A tumor registrar is abstracting a case where pathology shows extension of the tumor into but not through the serosa of the colon. Which T category applies in AJCC 8th edition?

    Answer: T3

    T3 colon tumors invade through the muscularis propria into pericolorectal tissues but do not penetrate the visceral peritoneum.

  4. Which receptor status combination confers the best prognosis in breast cancer?

    Answer: ER+/PR+/HER2-

    ER+/PR+/HER2- tumors are hormone receptor-positive and HER2-negative, associated with the best overall prognosis among the major subtypes.

  5. In the AJCC staging system, clinical staging (cTNM) is based on information available before which event?

    Answer: First definitive treatment

    Clinical staging uses all information obtained before the first definitive treatment, including physical exam, imaging, and biopsy results.

  6. For melanoma, which prognostic factor is most important for T category assignment in AJCC 8th edition?

    Answer: Breslow thickness and ulceration

    Breslow thickness (measured in millimeters) and presence of ulceration are the primary determinants of the T category in AJCC 8th edition melanoma staging.

  7. What does 'resection margin status' (R classification) describe in surgical pathology reports?

    Answer: Presence of residual tumor after surgical resection

    The R classification documents whether residual tumor remains after surgery: R0 (no residual), R1 (microscopic residual), or R2 (macroscopic residual).